Kris V Kowdley Selected Research

obeticholic acid

9/2021	Horizon scanning of therapeutic modalities for nonalcoholic steatohepatitis.
1/2021	Anxiety and Depression in Patients with Primary Biliary Cholangitis: Current Insights and Impact on Quality of Life.
5/2020	Obeticholic acid for the treatment of nonalcoholic steatohepatitis.
1/2020	A randomized, placebo-controlled, phase II study of obeticholic acid for primary sclerosing cholangitis.
1/2020	Current and potential treatments for primary biliary cholangitis.
12/2019	Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial.
12/2019	A Pilot Genome-Wide Analysis Study Identifies Loci Associated With Response to Obeticholic Acid in Patients With NASH.
1/2019	Relationship between three commonly used non-invasive fibrosis biomarkers and improvement in fibrosis stage in patients with non-alcoholic steatohepatitis.
1/2019	Factors Associated With Histologic Response in Adult Patients With Nonalcoholic Steatohepatitis.
1/2019	Obeticholic acid in primary biliary cholangitis: where we stand.

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Kris V Kowdley Research Topics

Disease

76	Fibrosis (Cirrhosis) 01/2022 - 04/2002
52	Non-alcoholic Fatty Liver Disease 01/2022 - 08/2003
33	Liver Diseases (Liver Disease) 01/2022 - 05/2002
31	Infections 05/2021 - 04/2002
28	Iron Overload 01/2022 - 09/2003
26	Hemochromatosis (Bronze Diabetes) 06/2022 - 04/2003
24	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 06/2022 - 11/2005
23	Chronic Hepatitis C 01/2019 - 04/2002
21	Inflammation (Inflammations) 05/2021 - 08/2008
17	Hepatitis C 01/2018 - 04/2002
13	Hepatocellular Carcinoma (Hepatoma) 01/2020 - 07/2003
12	Chronic Hepatitis B 04/2013 - 05/2002
11	End Stage Liver Disease 01/2021 - 02/2003
10	Sclerosing Cholangitis 06/2022 - 02/2008
10	Pruritus (Itching) 06/2022 - 03/2015
9	Liver Cirrhosis (Hepatic Cirrhosis) 05/2021 - 05/2009
9	Neoplasms (Cancer) 04/2017 - 11/2002
8	Alcoholic Fatty Liver 01/2022 - 01/2009
8	Fatigue 07/2021 - 04/2013
8	Fatty Liver 11/2019 - 01/2009
7	Insulin Resistance 01/2022 - 09/2010
7	Disease Progression 01/2021 - 04/2002
6	Hemorrhage 01/2021 - 05/2002
5	Obesity 07/2014 - 08/2003
4	Hyperferritinemia 01/2022 - 05/2004
4	Hepatic Encephalopathy 01/2021 - 09/2005
4	Ascites 01/2021 - 03/2003
4	Liver Failure 01/2021 - 05/2002
4	Diabetes Mellitus 11/2019 - 05/2009
4	Anemia 01/2018 - 09/2012
4	Nausea 05/2013 - 04/2013
4	Varicose Veins (Varicose Vein) 07/2010 - 11/2005
4	Hepatitis B 08/2008 - 04/2003
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 02/2020 - 01/2018
3	Cholestasis 01/2019 - 05/2012
3	Iron Deficiencies 07/2014 - 05/2004
3	Type 2 Diabetes Mellitus (MODY) 06/2014 - 11/2003
3	Body Weight (Weight, Body) 05/2014 - 01/2014

Drug/Important Bio-Agent (IBA)

54	IronIBA 01/2022 - 04/2002
22	Ribavirin (Virazole)FDA LinkGeneric 02/2019 - 04/2002
20	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 01/2021 - 03/2004
19	Biomarkers (Surrogate Marker)IBA 06/2022 - 04/2002
16	obeticholic acidIBA 09/2021 - 03/2015
14	SofosbuvirIBA 01/2017 - 04/2013
13	nasIBA 01/2022 - 01/2009
13	Alanine Transaminase (SGPT)IBA 10/2021 - 08/2008
13	HepcidinsIBA 05/2021 - 02/2004
13	Antiviral Agents (Antivirals)IBA 02/2019 - 11/2005
12	Ferritins (Ferritin)IBA 01/2019 - 04/2002
11	InterferonsIBA 01/2018 - 04/2002
10	Alkaline PhosphataseIBA 12/2021 - 09/2010
9	Bile Acids and Salts (Bile Acids)IBA 01/2022 - 07/2010
8	Pharmaceutical PreparationsIBA 01/2022 - 11/2004
8	BilirubinIBA 12/2021 - 11/2005
8	EnzymesIBA 01/2020 - 04/2003
8	Protease Inhibitors (Protease Inhibitor)IBA 01/2017 - 09/2012
8	sofosbuvir drug combination ledipasvirIBA 01/2017 - 05/2014
7	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2021 - 05/2010
7	Transaminases (Aminotransferases)IBA 08/2015 - 04/2002
6	Triglycerides (Triacylglycerol)IBA 10/2021 - 11/2003
6	Vitamin E FDA LinkGeneric 05/2021 - 01/2009
6	paritaprevirIBA 02/2019 - 01/2013
6	NucleotidesIBA 01/2017 - 07/2011
6	Transferrin (beta 2 Transferrin)IBA 03/2014 - 04/2002
6	Lamivudine (Epivir)FDA Link 01/2007 - 05/2002
5	Pioglitazone (Actos)FDA Link 05/2021 - 03/2007
5	acceleratory factor from growth hormone (AcG)IBA 02/2021 - 05/2015
5	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 02/2020 - 09/2010
5	dasabuvirIBA 02/2019 - 01/2013
5	Ritonavir (Norvir)FDA Link 02/2019 - 01/2013
4	cilofexorIBA 06/2022 - 01/2019
4	Glucose (Dextrose)FDA LinkGeneric 10/2021 - 01/2010
4	LipidsIBA 10/2021 - 08/2016
4	CollagenIBA 01/2021 - 01/2020
4	Insulin (Novolin)FDA Link 01/2021 - 01/2010
4	LigandsIBA 12/2019 - 03/2015
4	ombitasvirIBA 02/2019 - 01/2014
4	Dietary IronIBA 01/2016 - 12/2003
4	CopperIBA 01/2014 - 12/2003
4	entecavir FDA Link 04/2013 - 01/2007
4	Hepatitis B e AntigensIBA 09/2012 - 04/2003
3	AdiponectinIBA 10/2021 - 02/2005
3	cenicrivirocIBA 09/2021 - 01/2018
3	Drug CombinationsIBA 07/2021 - 01/2019
3	selonsertibIBA 07/2021 - 01/2019
3	Interleukin-6 (Interleukin 6)IBA 05/2021 - 07/2014
3	metal transporting protein 1 (ferroportin)IBA 01/2021 - 02/2005
3	SodiumIBA 01/2021 - 03/2003
3	DiureticsIBA 01/2021 - 03/2003
3	RNA (Ribonucleic Acid)IBA 01/2021 - 05/2013
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 05/2005
3	Protons (Proton)IBA 01/2019 - 01/2007
3	daclatasvirIBA 11/2016 - 04/2015
3	ledipasvirIBA 01/2016 - 05/2014
3	peginterferon alfa-2a (Pegasys)FDA Link 06/2013 - 05/2013

Therapy/Procedure

51	Therapeutics 06/2022 - 05/2002
32	Liver Transplantation 06/2022 - 05/2002
4	Transplantation 02/2020 - 11/2005
4	Duration of Therapy 03/2017 - 07/2007
3	Cell Transplantation 01/2016 - 02/2009